Major Challenges in Nanotechnology

At present, nanotechnology has been widely applied to the area of drug development. Nanoparticle-based therapeutics has the ability to overcome biological barriers and to deliver hydrophobic drugs and biologics effectively to the target sites of disease. The complexity of nanoparticles as multi-component 3D structures require careful design and engineering and reproducible scale-up and manufacturing process to achieve a consistent product. The safety and efficacy of nanoparticle-based medicines can be influenced by minor variations in multiple parameters and need to be carefully examined in preclinical and clinical examinations. Finally, nanoparticle-based medicines may have to represent additional development challenges and regulatory considerations compared with conventional medicines. Efforts are being made to produce unique category of therapeutic agents while there is generally a lack of regulatory standards in the examination of nanoparticle-based medicines.

  • Rapid DNA sequencing
  • Single-stranded genomic DNA or RNA
  • Organic and inorganic nano composites
  • Safety and risk assessment of nanotechnology

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