Nanotechnology for Targeted Drug Delivery
Nano drug delivery systems can be used to tune and regulate release pharmacokinetics, pharmacodynamics, solubility, immunocompatibility, cellular uptake, biodistribution and by reducing toxicity these will enhances therapeutic index of traditional pharmaceuticals. They can be used to deliver both small-molecular and macromolecular drugs. These nanoparticles mediated sustained release of drugs offer an advantage that the targeted delivery of drugs in the body is required to prevent the release of therapeutics at non-specific sites and unwanted side-effects. The conjugation of targeting moieties with drug-loaded nanoparticles can be used for receptor-mediated and targeted delivery. Such targeted nanoparticles have the characteristics of a perfect drug delivery system that tends to improve the therapeutic activity while reducing the toxic side effects of drugs.
- Development of novel nanocarriers
- Nanostructured materials and polymers
- Polymeric nanocapsules
- Biodegradable nanogels
- Nanoscale systems
- Tumor-specific targeting with nanocarriers
- Nanocarrier-based protein/peptide delivery systems
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