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Congcong Lin


Congcong Lin

Hong Kong Baptist University, Hong Kong

Biography

Congcong Lin has her expertise in development of novel drug delivery system and passion in improving the health and wellbeing. Her main research direction is design and evaluation of the new drug delivery system based on the special microenvironment of tumor sites to achieve targeted drug delivery and precision therapy. She has developed triptolide-loaded liposomes decorated with anti-carbonic anhydrase IX (CA IX) antibody targeting CA IX confined to cancerous cells to increase the accumulation of the drug loaded liposomes at tumor sites and combining the advantage of pulmonary delivery for better retention of active ingredients in lung. This study provides insight into targeted and sustained delivery of a toxic drug through CA IX-decorated liposomes via the pulmonary route for lung cancer therapy.

Abstract

Abstract : Targeted drug delivery with dual-ligand decorated liposomes by anti-CA IX antibody and tumor homing cell penetrating peptide in 2D and 3D lung cancer cells